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J Mater Sci Mater Med ; 32(9): 101, 2021 Aug 18.
Artigo em Inglês | MEDLINE | ID: mdl-34406528

RESUMO

Nanoparticles (NPs) have a wide range of applications in various areas. For health application, cytotoxicity tests are used to ensure its efficiency and safety. In this paper, ZnFe2O4, CoFe2O4, Zn0.5Co0.5Fe2O4 NPs were synthesized, characterized and their antibacterial properties were evaluated. The Sol-Gel method was used to synthesize the NPs. Their electronic and crystallographic structures were characterized by Fourier Transform Infrared Spectroscopy Analysis (FTIR), X-ray fluorescence (XRF), X-Ray Diffraction (XRD), and Transmission Electron Microscopy (TEM). To perform the antibacterial evaluation, ferrites were dispersed through nanoemulsion to prevent the crystals from accumulating together. Then the evaluation was performed through microdilution in a 96-well plate and diffusion in agar disc in contact with 3 different strains of Staphylococcus aureus and Escherichia coli. It demonstrated that the Sol-Gel method was efficient to synthesize NPs with suitable sizes for health application. All synthesized NPs showed the inhibition of bacterias with different concentrations used.


Assuntos
Antibacterianos/química , Antibacterianos/farmacologia , Nanopartículas Metálicas/química , Metais/química , Óxidos/química , Animais , Bactérias/efeitos dos fármacos , Sobrevivência Celular , Chlorocebus aethiops , Difusão , Escherichia coli , Química Verde/métodos , Concentração Inibidora 50 , Testes de Sensibilidade Microbiana , Microscopia Eletrônica de Transmissão , Tamanho da Partícula , Transição de Fase , Espectroscopia de Infravermelho com Transformada de Fourier , Staphylococcus aureus , Testes de Toxicidade , Células Vero , Difração de Raios X
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